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oxaprozin (generic name)

(ox a PROE zin): An NSAID - It is used to reduce swelling and to treat pain

oxaprozin

What is this medicine?
OXAPROZIN (ox a PROE zin) is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. It may be used for for rheumatoid arthritis, osteoarthritis, and juvenile rheumatoid arthritis.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What is the price of this medication and similar alternatives?

This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 09/2009. For the most current and up-to-date pricing information, please visit www.drugstore.com. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.

Daypro 600MG Tablets PFIZER U.S.60/$149.9 or 180/$436.52
Oxaprozin 600MG Tablets APOTEX90/$25.99 or 180/$45.97
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • chest pain
  • difficulty breathing or wheezing
  • nausea or vomiting
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • severe abdominal pain
  • slurred speech or weakness on one side of the body
  • unexplained weight gain or swelling
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • dizziness
  • headache
  • heartburn
How should I use this medicine?
Take this medicine by mouth with food and with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Long-term, continuous use may increase the risk of heart attack or stroke.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.

Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
  • cidofovir
  • ketorolac
  • methotrexate
  • pemetrexed

This medicine may also interact with the following medications:

  • alcohol
  • aspirin and aspirin-like medicines
  • cimetidine
  • cyclosporine
  • diuretics
  • glyburide
  • lithium
  • medicines for high blood pressure
  • medicines that affect platelets
  • medicines that treat or prevent blood clots like warfarin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • ranitidine
  • steroid medicines like prednisone or cortisone
Who should NOT use this medication?

  • Known hypersensitivity to oxaprozin or any ingredient in the formulation.
  • History of asthma, urticaria, or other sensitivity reaction precipitated by aspirin or other NSAIAs.
  • Treatment of perioperative pain in the setting of CABG surgery.

What should I watch for while using this medicine?
Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.

This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.

Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.

This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
  • asthma, especially aspirin sensitive asthma
  • coronary artery bypass graft (CABG) surgery within the past 2 weeks
  • drink more than 3 alcohol-containing drinks a day
  • heart disease or circulation problems like heart failure or leg edema (fluid retention)
  • high blood pressure
  • kidney disease
  • liver disease
  • stomach bleeding or ulcers
  • an unusual or allergic reaction to oxaprozin, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
Can I stop taking the medication if I feel better?
If you are taking an analgesic for pain and you are no longer experiencing the pain you may stop using the medication. In general, pain medications are to be used on an “as needed” basis.
I am on so many medications; do I have to take them all?
This is called polypharmacy—many different medications being used at the same time by one person. Sometimes, being on multiple medications is acceptable and appropriate but at other times it may be problematic. If you are receiving your medications from multiple physicians you need to ensure that they all know what medications you are taking. The best way to do this is to make a list of all the medications you are currently using, including all nutritional supplements, homeopathic remedies, vitamins and over-the-counter drugs (if possible, also include all the diseases you have been diagnosed with). Give a copy to every doctor who takes care of you so they have it on file, this way they can avoid duplicating medications and perhaps even try to consolidate some. After every doctor's visit remember to update the list accordingly. Also, as much as you possibly can, try to use the same pharmacy to fill all your prescriptions, this way any potential drug interactions can be caught and averted.
Where can I get more information?
More Information

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