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doxepin (generic name)

(DOX e pin): A topical antihistamine - It is used on the skin to treat itching caused by certain types of skin disorders

doxepin

What is this medicine?
DOXEPIN (DOX e pin) is used to treat depression and anxiety.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What is the price of this medication and similar alternatives?

This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 09/2009. For the most current and up-to-date pricing information, please visit www.drugstore.com. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.

Doxepin HCl 10MG Capsules PAR90/$19 or 180/$23.99
Doxepin HCl 10MG/ML Concentrate TEVA PHARMACEUTICALS USA120/$16 or 360/$45.97
Doxepin HCl 100MG Capsules PAR30/$13.99 or 60/$18.98
Doxepin HCl 150MG Capsules PAR30/$25.99 or 90/$55.95
Doxepin HCl 25MG Capsules PAR60/$13.99 or 120/$19.98
Doxepin HCl 50MG Capsules PAR60/$14.99 or 180/$25.97
Doxepin HCl 75MG Capsules PAR30/$8.99 or 90/$21.97
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
  • abnormal production of milk in females
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breast enlargement in both males and females
  • breathing problems
  • confusion, hallucinations
  • excessive thirst and/or hunger
  • fast, irregular or pounding heartbeat
  • fever with sweating
  • muscle stiffness, or spasms
  • passing urine more times in a day
  • seizures
  • suicidal thoughts or other mood changes
  • swelling of the testicles
  • tingling, pain, or numbness in the feet or hands
  • trouble passing urine or change in the amount of urine
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in sex drive or performance
  • constipation, or diarrhea
  • nausea, vomiting
  • weight gain or loss

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
  • arsenic trioxide
  • certain medicines used to regulate abnormal heartbeat or to treat other heart conditions
  • cisapride
  • halofantrine
  • levomethadyl
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • other medicines for mental depression
  • phenothiazines like perphenazine, thioridazine and chlorpromazine
  • pimozide
  • procarbazine
  • sparfloxacin
  • St. John's Wort
  • ziprasidone

This medicine may also interact with the following medications:

  • cimetidine
  • tolazamide

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Who should NOT use this medication?

  • Although the manufacturers do not state that doxepin is contraindicated in patients receiving MAO inhibitors, concurrent or recent (i.e., within 2 weeks) therapy with MAO inhibitors generally is contraindicated in patients receiving TCAs. (See MAO Inhibitors under Interactions.)
  • Glaucoma or urinary retention.
  • Known hypersensitivity to doxepin or other dibenzoxepin-derivative TCAs.

What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. It can take several days before you feel the full effect of this medicine. If you have been taking this medicine regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose or you may get severe side effects. Ask your doctor or health care professional for advice. Even after you stop taking this medicine it can still affect your body for several days.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

Do not treat yourself for coughs, colds, or allergies without asking your doctor or health care professional for advice. Some ingredients can increase possible side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
  • bipolar disorder or schizophrenia
  • difficulty passing urine
  • glaucoma
  • kidney or liver disease
  • thoughts or plans of suicide or a previous suicide attempt or family history of suicide attempt
  • an unusual or allergic reaction to doxepin, sulfites, tartrazine dye, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
Can I stop taking the medication if I feel better?
As a general rule, you should always take your medications exactly as prescribed and do not change the dosage or stop taking the medication without first discussing it with your healthcare provider.
I am on so many medications; do I have to take them all?
This is called polypharmacy—many different medications being used at the same time by one person. Sometimes, being on multiple medications is acceptable and appropriate but at other times it may be problematic. If you are receiving your medications from multiple physicians you need to ensure that they all know what medications you are taking. The best way to do this is to make a list of all the medications you are currently using, including all nutritional supplements, homeopathic remedies, vitamins and over-the-counter drugs (if possible, also include all the diseases you have been diagnosed with). Give a copy to every doctor who takes care of you so they have it on file, this way they can avoid duplicating medications and perhaps even try to consolidate some. After every doctor's visit remember to update the list accordingly. Also, as much as you possibly can, try to use the same pharmacy to fill all your prescriptions, this way any potential drug interactions can be caught and averted.
Where can I get more information?
More Information

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