What is this medicine? DICLOFENAC; MISOPROSTOL (dye KLOE fen ak; mye soe PROST ole) is a combination of two different drugs. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. Misoprostol protects the stomach against ulcers. This medicine is used for arthritis in people who are at high risk for stomach ulcers from NSAID treatment.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
How should I use this medicine? Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Long-term, continuous use may increase the risk of heart attack or stroke.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.
What should I watch for while using this medicine? Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from this medicine. Ulcers and bleeding can happen without warning symptoms and can cause death.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
This medicine can cause you to bleed more easily. Try to avoid damage to your teeth and gums when you brush or floss your teeth.
If you are female, do not use this medicine if you are pregnant. Do not get pregnant while taking this medicine and for at least one month (one full menstrual cycle) after stopping this medicine. If you can have children, use a reliable form of birth control while taking this medicine. Talk to your doctor about birth control options. If you become pregnant, think you are pregnant, or want to become pregnant, immediately call your doctor for advice.
Can I stop taking the medication if I feel better? If you are taking an analgesic for pain and you are no longer experiencing the pain you may stop using the medication. In general, pain medications are to be used on an “as needed” basis.
I am on so many medications; do I have to take them all? This is called polypharmacymany different medications being used at the same time by one person. Sometimes, being on multiple medications is acceptable and appropriate but at other times it may be problematic. If you are receiving your medications from multiple physicians you need to ensure that they all know what medications you are taking. The best way to do this is to make a list of all the medications you are currently using, including all nutritional supplements, homeopathic remedies, vitamins and over-the-counter drugs (if possible, also include all the diseases you have been diagnosed with). Give a copy to every doctor who takes care of you so they have it on file, this way they can avoid duplicating medications and perhaps even try to consolidate some. After every doctor's visit remember to update the list accordingly. Also, as much as you possibly can, try to use the same pharmacy to fill all your prescriptions, this way any potential drug interactions can be caught and averted.