Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Avoid in individuals with a known allergy or hypersensitivity to ignatia or to a member of the Loganiaceae family.
Side Effects and Warnings
Ignatia is possible safe when used as a homeopathic remedy. However, due to the strychnine content, taking Ignatius bean by mouth may cause restlessness, anxiety, heightened sense perception, enhanced reflexes, equilibrium disorders, painful back and neck stiffness, twitching, spasms of jaw and neck muscles, convulsions triggered by visual or touch stimulation with possible opisthonos (rigid muscle contraction), extreme muscle tension, hyperthermia (abnormally high body temperature), seizures, metabolic acidosis (blood is too acidic), fatal cardiac arrest, rhabdomyolysis (degeneration of skeletal muscle), agitation and difficulty breathing after respiratory spasms. The U.S. Food and Drug Administration (FDA) banned strychnine from non-regulated products in 1989.
Avoid ignatia in patients with liver disease since strychnine accumulates in individuals with liver damage and can cause further damage. Ignatia may also cause myoglobinuric renal failure, and caution is advised in patients with compromised kidney function.
This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Cathy DeFranco Kirkwood, MPH, CCCJS-MAC (MD Anderson Cancer Center); Chi Dam, PharmD (Northeastern University); Nicole Giese, MS (Boston University); Dana A. Hackman, BS Northeastern University; Tamara Milkin, PharmD (Northeastern University); Lisa Scully, PharmD (University of Rhode Island); Erica Seamon, PharmD (Nova Southeastern University); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Wendy Weissner, BA (Natural Standard Research Collaboration); Shannon Welch, PharmD (Northeastern University).
Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Oberbaum M, Schreiber R, Rosenthal C, et al. Homeopathic treatment in emergency medicine: a case series. Homeopathy 2003;92(1):44-47.
Wasilewski BW. Homeopathic remedies as placebo alternatives--verification on the example of treatment of menopause-related vegetative and emotional disturbances. Sci Eng Ethics 2004;10(1):179-188.
Remember, keep this and all other medicines out of the reach of children,
never share your medicines with others, and use this medication only for the indication prescribed.