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garlic (generic name)

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Garlic (Allium sativum L.)

Category

Herbs & Supplements

Alternate Title

Allium sativum

Synonyms

2-propenesulfenic acid, aged garlic extract, aglio, ail, ail commun, ajo, ajoene, akashneem, alisat, alk(en)yl thiosulfates, allicin, Allicor®, Allii sativi bulbus, alliinase, allium, allitridium, allyl mercaptan, alubosa elewe, Amaryllidaceae (family), ayo-ishi, ayu, banlasun, camphor of the poor, clove garlic, da-suan, dai toan, dasuan, dawang, diallyl, diallyl disulphide, diallyl sulfide, diallyl sulphide, diethyl disulfide, diethyl hexasulfide, diethyl monosulfide, diethyl pentasulfide, diethyl tetrasulfide, diethyl trisulfide, dipropyl disulphide, dipropyl sulphide, dra thiam, (E)-ajoene, foom, garlic clove, garlic corns, garlic extract, garlic oil, garlic paste, garlic powder extract, Gartenlauch, hom khaao, hom kia, hom thiam, hua thiam, Karinat®, kesumphin, kitunguu-sumu, knoblauch, kra thiam, Krathiam, krathiam cheen, krathiam khaao, Kwai®, Kyolic®, l'ail, lahsun, lai, la-juan, lasan, lashun, la-suan, lasun, lasuna, lauch, lay, layi, lehsun, lesun, Liliaceae (family), lobha, majo, methyl allyl, naharu, nectar of the gods, Ninniku, pa-se-waa, poor man's treacle, rason, rasonam, rasun, rust treacle, rustic treacles, S-alk(en)yl cysteine sulfoxide, S-allylcysteine (SAC), seer, skordo, sluon, stinking rose, sudulunu, tafanuwa, ta-suam, ta-suan, tellagada, Tellagaddalu, thiam, thioallyl derivative, thiosulfinates, toi thum, tum, umbi bawang putih, vallaippundu, Velluli, vellulli, verum, vinyl dithiin, vinyldithiin, (Z)-ajoene.

Background

Numerous controlled trials have examined the effects of oral garlic on serum lipids. Long-term effects on lipids or cardiovascular morbidity and mortality remain unknown. Other preparations (such as enteric-coated or raw garlic) have not been well studied.

Small reductions in blood pressure (<10 millimeters of mercury), inhibition of platelet aggregation, and enhancement of fibrinolytic activity have been reported, and may exert effects on cardiovascular outcomes, although evidence is preliminary in these areas.

Numerous case-control/population-based studies suggest that regular consumption of garlic (particularly unprocessed garlic) may reduce the risk of developing several types of cancer, including gastric and colorectal malignancies. However, prospective controlled trials are lacking.

Multiple cases of bleeding have been associated with garlic use, and caution is warranted in patients at risk of bleeding or prior to some surgical/dental procedures. Garlic does not appear to significantly affect blood glucose levels.

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