Licensed from

pentoxifylline (generic name)

Trental (brand name)

(pen tox I fi leen): A coagulation modifier - It improves blood flow
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Pentoxifylline Oral tablet

What is this medicine?

PENTOXIFYLLINE (pen tox I fi leen) improves blood flow. This medicine helps to decrease the pain, discomfort, or cramps you can get from having poor circulation in your legs.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole. Do not crush or chew. Take with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You may feel some benefit after 2 to 4 weeks of treatment, but it can take up to 8 weeks before you get the full benefit.

Smoking tobacco or marijuana can make your condition worse by further narrowing the blood vessels. Do not smoke.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • agitation
  • chest pain, fast or irregular heartbeat
  • flushing
  • seizures

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Last Updated

July 20, 2009

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