What is this medicine?

KETOROLAC (kee toe ROLE ak) is a non-steroidal anti-inflammatory drug (NSAID). It is used for a short while to treat moderate to severe pain, including pain after surgery. It should not be used for more than 5 days.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• asthma
• bleeding problems like hemophilia
• cigarette smoker
• drink more than 3 alcohol containing drinks a day
• heart disease or circulation problems such as heart failure or leg edema (fluid retention)
• high blood pressure
• kidney disease
• liver disease
• stomach bleeding or ulcers
• an unusual or allergic reaction to ketorolac, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not take more than the recommended dose.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 16 years of age for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• aspirin and aspirin-like medicines
• cidofovir
• methotrexate
• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
• pemetrexed
• probenecid

This medicine may also interact with the following medications:

• alcohol
• alendronate
• alprazolam
• carbamazepine
• cyclosporine
• diuretics
• flavocoxid
• fluoxetine
• ginkgo
• lithium
• medicines for high blood pressure like enalapril
• medicines that affect platelets like pentoxifylline
• medicines that treat or prevent blood clots like heparin, warfarin
• muscle relaxants
• phenytoin
• steroid medicines like prednisone or cortisone
• thiothixene