Licensed from

histrelin (generic name)

(his TREL in): A gonadotropin releasing hormone - It is used to treat the symptoms of advanced prostate cancer
of 2

Histrelin Acetate Implant

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. During the first week, your symptoms may get worse but then will start to get better as you continue your treatment. You may get hot flashes, increased bone pain, increased difficulty passing urine, or an aggravation of nerve symptoms. Discuss these effects with your doctor or health care professional. Some of these may get better with continued use of this medicine.

Rarely, the implant can be expelled from the body through the original incision site. It is possible that you may see the implant being expelled, or rarely, the implant may be expelled without you noticing it. If you believe the implant has been expelled from your body, call your doctor.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • blood in your urine
  • changes in vision
  • loss of bladder or bowel control
  • new or worse bone pain
  • pain at the insertion site
  • severe headache
  • trouble passing urine or change in the amount of urine
  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • breast enlargement
  • change in sex drive or performance
  • constipation
  • hot flashes (sudden feelings of warmth or sweating)
  • redness or irritation at the insertion site
  • testicles become smaller
  • trouble sleeping
  • weight gain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

of 2

Last Updated

May 04, 2009

Follow Yahoo! Health on and become a fan on

Follow @YahooHealth on