Licensed from

APAP/guaifenesin/phenylephrine (generic name)

(a set a MEE noe fen; gwye FEN e sin; fen il EF rin): An upper respiratory combination - It is used to treat fever, aches and pains, and congestion from a cold or allergy
of 2

Acetaminophen, Guaifenesin, Phenylephrine Hydrochloride Oral tablet

What is this medicine?

ACETAMINOPHEN; GUAIFENESIN; PHENYLEPHRINE (a set a MEE noe fen; gwye FEN e sin; fen il EF rin) is a combination of a pain reliever, expectorant and decongestant. It is used to treat fever, aches and pains, and congestion from a cold or allergy. It is also used to treat a dry cough. This medicine will not treat an infection.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the label. Tablets may be broken in half. Do not crush or chew. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction to this medicine and need smaller doses.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

This medicine may also interact with the following medications:

  • furazolidone
  • imatinib
  • isoniazid
  • linezolid
  • mecamylamine
  • medicines for chest pain, heart disease, blood pressure, or heart rhythm problems
  • medicines for depression, anxiety, or psychotic disturbances
  • other medicines for allergies or colds
  • reserpine
  • some medicines used for sleep during surgery
  • St. John's Wort
  • theophylline

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

of 2

Last Updated

March 17, 2009

Follow Yahoo! Health on and become a fan on

Follow @YahooHealth on