Medications that affect the bone marrow, including cancer drugs (chemotherapy), chloramphenicol (Chloromycetin), anticonvulsant medications, and antipsychotic drugs (Thorazine, Prolixin, and other phenothiazines). In hematopoietic stem cell transplantation (HSCT), high levels of total body irradiation (TBI) or chemotherapy are used to kill cancer cells, or these treatments may be combined. Two types of HSCT treatments are bone marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT). During the treatment process, the patient's normal bone marrow stem cells are killed along with the cancer cells. The stem cells are not able to mature into immune cells such as neutrophils, causing neutropenia. To reduce neutropenia, the normal stem cells from the patient may be removed prior to treatment and given back at a later time. Cells can also be supplied from another donor.
Hereditary and congenital disorders that affect the bone marrow, including familial neutropenia, cyclic neutropenia, and infantile agranulocytosis.