Lysergic Acid Diethylamide Health Article

Interactions

LSD flashbacks can be spurred by use of drugs such as marijuana. Preliminary evidence suggests serotonin reuptake inhibitors like Prozac and Zoloft may also exacerbate the LSD flashback syndrome.

PERIODICALS

Aghajanian, G. K. and G. J. Marek. "Serotonin and Hallucinogens." Neuropsychopharmacology (1999): 16S-23S

Markel, H., A. Lee, R. Holmes, and E. Domino. "LSD Flashback Syndrome Exacerbated By Selective Serotonin Reuptake Inhibitor Antidepressants In Adolescents." Journal of Pediatrics (November 1994): 817-819.

ORGANIZATIONS

National Clearinghouse for Alcohol and Drug Information. 11426 Rockville Pike, Suite 200, Rockville, MD. 20852. (800) 729-6686. <http://www.health.org>.

National Institute on Drug Abuse. P.O. Box 30652, Bethesda, MD. 20824-0652. (888) 644-6432. <http://www.drugabuse.gov>.

U.S. Department of Justice, Drug Enforcement Administration. 2401 Jefferson Davis Highway, Alexandria, VA 22301. (888) 644-6432. <http://www.usdoj.gov/dea>.

Ann Quigley

KEY TERMS

Cerebral cortex—Brain region responsible for reasoning, mood, and perception.

Hallucinogen—A drug that distorts sensory perceptions and disturbs emotion, judgment, and memory.

Hallucinogen persisting perception disorder (HPPD)—The recurrence of LSD effects after the drug experience has ended.

Locus ceruleus—Brain region that processes sensory signals from all areas of the body.

Neurotransmitter—Chemical compound in the brain that transmits signals from one nerve cell to another.

Serotonin—A neurotransmitter that modulates the actions of other neurotransmitters in the brain.