When a heart attack
strikes, the absence of oxygen-containing blood damages and kills heart muscle
cells.
As you might expect,
as the time of blockage lengthens, the more cell damage and cell death occurs.
Heart muscle can be saved from destruction, however, through rapid restoration
of blood flow (reperfusion). This is possible by reopening occluded
arteries with a balloon (angioplasty) or bypassing them (coronary artery bypass
surgery). The key is getting this done quickly. Let's look at why time is so
important.
Guidelines from the
ACC and the AHA
Guidelines from the American College of Cardiology (ACC) and
the American Heart Association (AHA) recommend that no longer than 90 minutes
elapse from the time that a heart attack patient arrives at a hospital and
reperfusion therapy is begun (referred to as door-to-balloon or DTB time).
Hospitals around the country have worked hard to provide the personnel and
equipment around the clock to comply with these guidelines. The capacity to
meet the recommendation is used nationally as an indicator of hospital quality.
Less than 90
minutes DTB time may not be helpful
A report in a recent
issue of Archives of Internal Medicine examined whether improvement in
DBT time reduced mortality from an acute ST-elevation heart attack (STEMI) at a
group of Michigan hospitals. The results were disappointing. Even though the
DTB time decreased from 113 minutes in 2003 to 76 minutes in 2008, and the
percentage of patients who received therapy in less than 90 minutes more than
doubled, there was no change in hospital mortality during this period. The
authors do not reach this conclusion in their discussion of the results, but it
seems obvious that the best efforts of hospitals are largely wasted if
considerable heart damage occurs during the delay between the beginning of a
heart attack and the arrival of patients at a prepared hospital.
Getting to the
hospital more quickly is critical
Earlier studies have
documented an average delay of two hours between the onset of symptoms and
presentation at a hospital for patients with STEMI heart attacks. And
these delay times have not decreased despite extensive public education
efforts. Another article in the same issue of the Archives of Internal
Medicine examined how long it took patients with a less severe type of heart
attack (non-STEMI) to get to a hospital. Hospital records of over 100,000
patients showed that 60 percent of them waited for more than two hours
after the onset of symptoms before they began to seek medical care.
Call 911 if you have heart attack
symptoms
Since heart attack victims are unable
to tell whether they are having a more or less severe heart attack, it is
critical for all people to follow the recommendations of the American Heart
Association: call 911 if symptoms of a heart attack are unchanged or worsen
after 5 minutes. ALL older men and women, but especially those diagnosed with
coronary heart disease, should know the symptoms of a heart attack.
Visit the American Heart
Association website to learn specifics about the symptoms of a heart
attack and how they can differ for men and women.