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Nephrogenic Diabetes Insipidus

Definition

Nephrogenic diabetes insipidus is a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to pass a large amount of urine. The tubules allow water to be removed from the body or reabsorbed.

See also: Diabetes insipidus - central

Symptoms

You may have intense or uncontrollable thirst, and crave ice water. You will produce large amounts of urine, usually more than 3 - 15 liters per day.

If you do not drink enough fluids, dehydration can result. Symptoms may include:

  • Dry mucous membranes
  • Dry skin
  • Sunken appearance to eyes
  • Sunken fontanelles (soft spot) in infants

Other symptoms that can occur due to inadequate fluids include:

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