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Graft Vs. Host Disease

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Definition

Graft-versus-host disease (GVHD) is a complication that can occur after a bone marrow transplant in which the newly transplanted material attacks the transplant recipient's body.

Symptoms

Symptoms in both acute and chronic GVHD range from mild to severe.

Common acute symptoms include:

Chronic symptoms may include:

Dry eyes and dry mouth
Hair loss
Hepatitis
Lung and digestive tract disorders
Skin rash

In both acute and chronic GVHD, the patient is very vulnerable to infections.

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